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Early study tests cancer drug before surgery in head and neck patients

NCT ID NCT00954226

First seen Sep 30, 2025 · Last updated Jun 18, 2026 · Updated 29 times

Summary

This early-phase study tested a drug called erlotinib in 48 people with head and neck cancer who were scheduled for surgery. The goal was to see how the drug affects certain markers in tumor tissue, not to cure the disease. Participants received either a standard or high dose of erlotinib before their operation, and researchers compared changes in a biomarker called phospho-Akt between the two groups.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

head and neck cancer head and neck carcinoma salivary gland cancer salivary gland carcinoma skin carcinoma skin squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.