Early study tests cancer drug before surgery in head and neck patients

NCT ID NCT00954226

First seen Sep 30, 2025 · Last updated May 01, 2026 · Updated 20 times

Summary

This early-phase study looked at whether giving the drug erlotinib before surgery could help treat head and neck cancer. 48 patients received either a standard or high dose of the drug, which works by blocking enzymes that help cancer cells grow. The main goal was to measure changes in a protein called phospho-Akt in tumor samples, not to cure the disease.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

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