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Why do some moms develop high blood pressure years later? oxford study seeks answers

NCT ID NCT06187012

Knowledge-focused Sponsor: University of Oxford Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study from the University of Oxford looks at why women who had high blood pressure during pregnancy are more likely to develop heart and blood vessel disease later in life. Researchers will follow 200 women who gave birth 10 to 25 years ago, using heart scans, exercise tests, and other measurements. The goal is to understand the long-term effects, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors understand why some women develop high blood pressure and heart disease after pregnancy, potentially leading to better screening or prevention strategies.
What could go wrong
This is an observational study, not a treatment trial. It may not find clear causes, and results may not apply to all women. It is small (200 participants) and early-stage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2023

Expected to finish

Nov 2042

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The investigators will study a group of 200 women at 10 to 25 years postpartum to extend data coverage over time and to ensure a broad representation of hypertensive disease state during mid-life in women. This will be achieved by a follow-up of participants from a previous study called Preeclampsia Vascular Study (PVS) (08/H0604/127). These women were originally seen at 5 to 15 years post-index hypertensive or normotensive pregnancy. If required, the investigators will restart their identification and recruitment methods, previously used in PVS, based on obstetric records to identify, and recruit additional women who had pregnancies 10 to 25 years prior, to ensure that the sample size is reached. All participants will undergo a standardised imaging protocol as described in the general overview.

Ages

30 to 70 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion Criteria * Participant is willing and able to give informed consent for participation in the study * Female who had a pregnancy 10 to 25 years prior * Able (in the investigator's opinion) and willing to comply with all study requirements. * Adequate understanding of verbal and written English Exclusion Criteria: * The participant may not enter the study if ANY of the following apply: * Over 10 weeks pregnant during the course of the study * Evidence of congenital heart disease or significant chronic disease relevant to cardiovascular or metabolic status * Any significant disease or disorder which, in the opinion of the investigator, might influence the participant's ability to participate in the study For exclusion of MRI component only: • Unsuitable for MRI based on the responses to the MRI screening form. The participant may still be included in other parts of the study.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder cerebrovascular disorder Disease Progression hypertension, pregnancy-induced hypertensive disorder preeclampsia vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiovascular diseases Cerebrovascular disorders Hypertension Vascular diseases

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Oxford Department of Cardiovascular Medicine

    RECRUITING

    Oxford, OX3 9DU, United Kingdom

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