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Can heat or contrast therapy ease your knee pain? new study finds out

NCT ID NCT07293195

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 28, 2026 · Updated 2 times

Summary

This study looked at whether adding heat therapy or contrast therapy (alternating hot and cold) to a specific exercise program helps people with patellofemoral pain syndrome, a common cause of front knee pain. Forty adults aged 18 to 40 with at least three months of knee pain took part. They received supervised sessions of either heat or contrast therapy along with Otago exercises, and researchers measured changes in pain, swelling, knee movement, and daily function.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Dec 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: 1. Patients aged 18-40 years experiencing pain in the front of the knee, including the peripatellar or retropatellar areas. 2. Patient having pain severity a minimum value of 4-7 on the numeric pain rating scale. 3. Participants presenting with anterior knee pain persisting for three months or longer. 4. Pre- diagnosed patients with positive patellar compression and Grind tests. 5. Patients with lateral patellar tracking. Exclusion criteria: 1. Pain having a duration of less than three months or patients with previous knee surgeries. 2. Recent engagement in structured lower-limb exercise or rehabilitation interventions. 3. Patients with pregnancy, malignancy or any neurological dysfunctions.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ghurki Trust Teaching Hospital

    Lahore, Punjab Province, 57000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.