Heat therapy may soothe jaw pain in TMD sufferers
NCT ID NCT07153107
First seen Jun 27, 2026 · Last updated Sep 15, 2026 · Updated 6 times
Summary
This study tests whether applying local heat to the jaw can reduce pain and fatigue caused by teeth clenching in people with chronic temporomandibular disorder (TMD). Ten adults with TMD will receive heat therapy and report their pain levels daily for 8 days. Researchers will compare their results to a matched group not receiving heat, aiming to identify who benefits most from this simple treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Provide signed and dated informed consent form. * Willing to comply with all study procedures and be available for the duration of study participation. * Be 18 years or older. * Have a minimum set of teeth present, be it natural, implant-supported or fixed prosthodontics: all anterior teeth (incisors, canines), at least one premolar, at least one molar (first or second molar; third molars not considered). * TMD-Pain screener score equal to or greater than 3 * Myalgia (masticatory muscle pain) based on clinical exam following the DC/TMD protocol * Concurrent arthralgia (TMJ pain) and/or headache attributed to TMD allowed * Myofascial pain must meet the following criteria: 1. Onset \>3 months, occurring \>15 days/month on average in the last three months from the screening session 2. Minimum of 10 jaw pain episodes since onset, each episode lasting at least 30 minutes and no less than 2 hours within the day, OR unremitting Exclusion Criteria: * Traumatic facial injury or surgery on the face/jaw, arms or hands; * Presence of pain related to dental and periodontal pathology; * Currently undergoing active orthodontic treatment; * Pregnant; * Has any of the following medical conditions by self-report: 1. Renal failure or dialysis, 2. Heart disease (examples: uncontrolled arrythmia or hypertension, cardiomyopathy) or heart failure, Non-allergic bronchospasm (chronic obstructive pulmonary disease and emphysema), 3. Diabetes (type I or II) that is not controlled with medication or diet, 4. Hyperthyroidism, 5. Uncontrolled seizures; * Used any injection therapy (e.g., tender or trigger point injections, steroid injections), acupuncture, biofeedback, or TENS for the management of facial/jaw pain within 2 weeks prior to the screening assessment; If undergoing botulinum toxin injections in the head and neck area, must be 3 months since last set of injections and refrain from this treatment until study participation has ended * History of major depression or other major psychiatric disorder requiring hospitalization within the last 6 months prior to the screening assessment; * History of treatment for drug or alcohol abuse within the last 12 months; * Current pain medication use (e.g., opioids, ibuprofen, acetaminophen) that cannot be stopped \<24 hours prior to each study visit; * Current use of medically prescribed muscle relaxants for the duration of study participation; * Other conditions/diseases associated with altered pain perception: neurological or development disorders (dementia, autism spectrum disorder), neoplasm, multiple sclerosis, trigeminal neuralgia; * Adults lacking capacity to provide informed consent for themselves; * Unable to understand instructions for study procedures in English. * Anything that would place the individual at increased risk or preclude the individual's full compliance with study procedures or completion of the study."
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Minnesota
Minneapolis, Minnesota, 55455, United States
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Other studies related to the condition(s) this trial covers.
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