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New drug combo aims to ease double Heart-Lung strain

NCT ID NCT07147114

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 24 times

Summary

This study tests whether adding macitentan to the standard drug dapagliflozin helps people with a specific type of heart failure that also affects the lungs. About 64 adults in South Korea will take the combination or a placebo for 24 weeks. Researchers will measure changes in blood vessel resistance, heart strain, walking ability, and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

  • Chonnam National University Hospital

    RECRUITING

    Gwangju, 61469, South Korea

  • Chungbuk National University Hospital

    NOT_YET_RECRUITING

    Chungju, 28644, South Korea

  • Chungnam National University Hospital

    RECRUITING

    Daejeon, 35015, South Korea

  • Gachon University Gil Hospital

    RECRUITING

    Incheon, 405-760, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Incheon Sejong Hospital

    NOT_YET_RECRUITING

    Incheon, 21080, South Korea

  • Keimyung University Dongsan Hospital

    RECRUITING

    Daegu, 42601, South Korea

  • Koera University Guro Hospital

    NOT_YET_RECRUITING

    Seoul, 08308, South Korea

  • Pusan National University Hospital

    RECRUITING

    Busan, 49241, South Korea

  • Pusan National University Yangsan Hospital

    NOT_YET_RECRUITING

    Yangsan, 50612, South Korea

  • Samsung Medical Center

    NOT_YET_RECRUITING

    Seoul, 06351, South Korea

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • The Catholic University of Korea, Seoul St.Mary

    RECRUITING

    Seoul, 06591, South Korea

  • Yonsei University Health System, Severance Hospital

    NOT_YET_RECRUITING

    Seoul, 03722, South Korea

  • Yonsei University, Wonju Severance Christian Hospital

    RECRUITING

    Wŏnju, 26426, South Korea

Conditions

Explore the condition pages connected to this study.