Pacemaker tweak may help heart failure patients breathe easier during exercise
NCT ID NCT07270536
First seen Jan 04, 2026
Summary
This study tests whether increasing the pacemaker rate during light exercise can lower pressure inside the heart for people with heart failure with preserved ejection fraction (HFpEF). Twenty participants will have their heart pressures measured at rest and while cycling, as the pacemaker rate is gradually increased. If successful, this could lead to a simple, drug-free way to reduce breathlessness and fatigue.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Jessa Ziekenhuis Hasselt
RECRUITINGHasselt, 3500, Belgium
Contact Email: •••••@•••••
Contact
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University Hospitals Leuven
RECRUITINGLeuven, 3000, Belgium
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
accelerated pacing with AV-delay optimization
What this could lead to
If it works, this could offer a simple, drug-free way to improve daily functioning and comfort for HFpEF patients with pacemakers.
What could go wrong
This is a very small, early study (20 participants) measuring immediate effects only. It may not translate to long-term benefits or apply to all HFpEF patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.