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Gum treatment may lower prostate inflammation and UTI risk

NCT ID NCT07438184

Disease control Sponsor: University of Salamanca Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether deep cleaning of the gums (non-surgical periodontal therapy) could reduce prostate-specific antigen (PSA) levels and urinary tract infections in men with both gum disease and chronic prostatitis or recurrent UTIs. Sixty men were split into three groups: one received gum treatment, one got only oral hygiene advice, and one had no gum care. Researchers measured PSA and urine infections over 120 days to see if treating gum inflammation helps the prostate.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
non-surgical periodontal therapy (deep cleaning of gums)
What this could lead to
If it works, this could point toward a simple, non-drug way to improve prostate health and reduce urinary infections in men with gum disease.
What could go wrong
This is a small, early-stage study with only 60 participants. The link between gum treatment and prostate health is still uncertain, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Jan 2024

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male participants aged 18 years or older * Diagnosis of chronic prostatitis (NIH category III) or recurrent urinary tract infections * Diagnosis of periodontitis according to the 2017 World Workshop classification * Ability to provide written informed consent Exclusion Criteria: * Antibiotic therapy within the previous 3 months * Systemic immunosuppressive disorders * History of prostate cancer * Ongoing periodontal treatment Severe systemic diseases affecting inflammatory status

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Conditions

The condition(s) this trial relates to.

chronic prostatitis periodontitis urinary tract infection urinary tract infections, recurrent, susceptibility to

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic prostatitis (CP) Periodontitis Urinary tract infections

Contacts and locations

Locations

  • University of Salamanca

    Salamanca, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.