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Gluten: friend or foe for elite athletes?

NCT ID NCT03101410

Knowledge-focused Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial investigates whether gluten consumption affects digestive comfort, quality of life, and physical performance in non-celiac athletes who train intensively. Participants, who are healthy and free of digestive diseases, will be randomly assigned to a gluten-containing or gluten-free diet. The study measures digestive symptoms, running performance, body composition, and gut microbiota to see if gluten sensitivity plays a role in athletic well-being.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Gluten (dietary intervention) versus gluten-free diet
What this could lead to
If gluten sensitivity is confirmed in athletes, it could lead to dietary strategies that improve digestive comfort and performance in non-celiac, high-intensity exercisers.
What could go wrong
This is a small, early-stage trial, and results may not apply to all athletes. The effects of gluten may be subtle or vary widely among individuals, and the study may not detect significant differences.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

51 people

The number who actually took part.

Started

Apr 2017

Finished

Mar 2018

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and female trained \>7h/week or more of 5 training/week * Member of a sports federation or medical certificate fewer 3 months * VO2 max estimated \>125% of the theoretical value * Regular consumption of gluten under different products * Healthy (apparently free of diseases) and without any medical treatment * Without digestive diseases and non-coeliac disease * Affiliated to National Health Insurance * Having normal capacity of training to enter in the study procedures * Having provided her written informed consent Exclusion Criteria: * Medicals or surgical histories, evaluated non compatible by the investigator * Diseases known * Antibiotherapy 2 months before the study * Gluten-free diet * Individual unable to give informed consent or refusing to sign informed consent * Being in exclusion on the National Volunteers Data file or refusing to be registered on the National Volunteers Data file * Currently participating or who having got 4500€ in this year before to have participating in another clinical trial

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Conditions

The condition(s) this trial relates to.

celiac disease intestinal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gluten-sensitive Intestinal diseases

Contacts and locations

Locations

  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63003, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.