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Exercise plus brain games may boost mood and mobility in frail seniors

NCT ID NCT07546734

Symptom relief Sponsor: University of Rome Foro Italico Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding core exercises and cognitive training to standard resistance training can improve quality of life in frail older adults. Thirty-two participants aged 65 and older completed 8 weeks of training. Researchers measured anxiety, depression, thinking skills, and balance. The goal is to find better ways to help older adults stay healthy and independent.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Resistance training, core exercises, and cognitive training
What this could lead to
If successful, this could point toward simple, non-drug exercise programs that improve mood, thinking, and physical function in frail older adults.
What could go wrong
This is a small, early study with only 32 participants. Results may not apply to all older adults, and the benefits may be modest or not last long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

Apr 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pre-frail/frail community-dwelling older adults * Aged ≥65 years * Community-dwelling Exclusion Criteria: * Cognitive decline (mini-mental state examination \<25/30) * Neurological disorders * Conditions impairing the ability to carry out exercise training (e.g., Parkinson's disease; multiple sclerosis; stroke) * Depression treated with pharmacological therapy or that have incurred in falls in the last two years.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Aging frailty Elderly Frail elderly Sarcopenia in elderly

Contacts and locations

Locations

  • University of Rome 'Foro Italico'

    Rome, Rome, 00135, Italy

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