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Exercise may shield you from fatty Food's harmful effects

NCT ID NCT07633704

Knowledge-focused Sponsor: George Washington University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a single session of exercise can protect the body from the negative effects of eating a high-fat diet for 24 hours. Fifty healthy adults aged 20-40 were randomly assigned to eat extra fatty foods with or without exercise. Researchers measured insulin resistance and how well the body switched between burning fats and carbs. The goal was to understand how exercise might help maintain metabolic health during periods of overeating.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Feb 2025

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Males or females between the ages of 20 and 40 years * A body mass index (BMI) of 20.0 - 29.9 kg/m2. * Low risk for risk of injury or health complications as determined by physical activity readiness questionnaire (PARQ). Exclusion Criteria: * Are currently taking any antioxidant supplementation (daily multivitamin not included), prescribed non-steroidal anti-inflammatory drugs (NSAIDS), antibiotics, steroids, or probiotics. * Are currently taking any medications for management of cholesterol, diabetes, or body weight/obesity, or are undergoing hormone therapy. * Are unwilling or unable to comply with study procedures, at the discretion of the investigators. * Are unwilling to have biospecimens (blood and urine) collected and stored (only blood) for future research. * Pregnant women - A urine pregnancy test will be conducted prior to any testing procedures. * A history of disordered eating, including anorexia nervosa, bulimia nervosa, binge eating disorder, or avoidant restrictive food intake disorder or deemed high-risk for disordered eating via questionnaire. * A history of gastrointestinal diseases, such as galactosemia, gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), Celiac disease, Crohn's disease, or lactose intolerance. * Individuals with known allergies to wheat or gluten, milk, soy, tree nuts (e.g., almonds, walnuts, pecans), or peanuts. * Deemed high risk for food insecurity via the Hunger Vital Sign screener. * Have followed a ketogenic diet within the last three months or have been told to avoid a high-fat diet by a medical provider for risk of cardiovascular disease. * Cardiorespiratory fitness (VO2max) below the 30th percentile for age and sex (measured at initial screening visit)

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Conditions

The condition(s) this trial relates to.

Insulin Resistance Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Insulin sensitivity/resistance

Contacts and locations

Locations

  • Milken Institute School of Public Health

    Washington D.C., District of Columbia, 20052, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.