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Exercise may cut breast cancer risk for women with dense tissue

NCT ID NCT06322888

First seen Nov 21, 2025 · Last updated Jun 19, 2026 · Updated 29 times

Summary

This study looks at whether a 12-week aerobic and resistance exercise program can lower breast cancer risk in women with dense breast tissue. Researchers will measure changes in blood markers and breast tissue samples from 46 physically inactive women aged 18-59. Participants are randomly assigned to either start exercising right away or join a waitlist control group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    ACTIVE_NOT_RECRUITING

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Exercise training program (aerobic and resistance exercise)

What this could lead to

If successful, this could show that regular exercise reduces breast cancer risk in women with dense breasts, pointing toward a simple, non-drug prevention strategy.

What could go wrong

This is a very small, early study (46 participants) looking at biological markers, not cancer itself. Results may not prove exercise prevents cancer, and the short 12-week program may not be enough to see lasting changes.

Conditions

The condition(s) this trial relates to.

breast neoplasm female breast carcinoma breast cancer prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.