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ICU patients may suffer less with new palliative care approach

NCT ID NCT06605079

Symptom relief Sponsor: Charite University, Berlin, Germany Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a program to improve palliative care in intensive care units (ICUs). The program includes remote consultations with palliative care experts, training for ICU staff, and checklists to identify patients who need extra support. Researchers will track 2040 patients to see if this approach reduces time in the ICU and overall suffering.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
palliative care consultation, staff training, and checklists
What this could lead to
If it works, this could improve quality of life for ICU patients and reduce time spent in intensive care.
What could go wrong
This is a behavioral intervention, not a drug, so results may vary by hospital. The trial is still recruiting, and benefits may not be dramatic or easy to measure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 2,040 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Patients: Inclusion Criteria: * Patients in ICU who can give consent and those who can not (via their authorized representative or legal guardian, also possible with delayed consent) * From 18 years * The leading cause of critical illness is not cancer * New admission on the participating ICU \> 72h * Assessment of the need for palliative care by the in-charge physi-cian of the ICU, because (1) there is a significant disagreement about ICU treatment or (2) because the physician considers ther-apy limitations for the patient or (3) the physician considers a benefit from specialized PC consultation for ICU physician, nurse, or patient or family. Exclusion Criteria: \- Patient is moribund and is expected to die within the next 24h Study cohort relatives: Inclusion criteria: \- At least one relative(s) of a patient. This may or may not be the legal representative, depending on national legislation. Exclusion criteria: * Refusal by the relative * Refusal of the patient to participate in the intervention study * \<18 years of age Cohort of employees: Inclusion criteria * Employed on the ITS as a doctor/nurse * Employed in the clinical center as a member of the palliative care consultation service Exclusion criterion Refusal to participate

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Palliative care

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    27 sites in 5 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CARITAS Klinik Maria Heimsuchung

    RECRUITING

    Berlin, Germany

  • Cardiothoracic Intensive Care Unit of the Onassis Cardiac Surgery Center

    RECRUITING

    Athens, Greece

  • Charité - Department of Anesthesiology and Intensive Care Medicine CBF

    RECRUITING

    Berlin, Germany

  • Department of Anesthesiology and Intensive Care Medicine (CCM/CVK),Charité - University Medicine Berlin

    RECRUITING

    Mitte, State of Berlin, Germany

  • Department of Anesthesiology and Intensive Care Medicine (CCM/CVK),Charité - University Medicine Berlin

    RECRUITING

    Wedding, State of Berlin, Germany

  • Department of Cardiology, Angiology and Intensive Care Medicine | CVK, Charité - University Berlin

    RECRUITING

    Berlin, Germany

  • Department of Intensive Care Medicine, Alexandra General Hospital

    RECRUITING

    Athens, Greece

  • Department of Intensive Care Medicine, Evaggelismos General Hospital

    RECRUITING

    Athens, Greece

  • Department of Intensive Care Medicine, University Hospital of Alexandroupolis

    RECRUITING

    Alexandroupoli, Greece

  • Department of Intensive Care Medicine, University Hospital of Heraklion

    RECRUITING

    Heraklion, Crete, Greece

  • Department of Intensive Care Medicine, University Hospital of Ioannina

    RECRUITING

    Ioannina, Greece

  • Department of Intensive Care Medicine, University Hospital of Patras

    RECRUITING

    Pátrai, Rio, Greece

  • Ev. Krankenhaus Paul-Gerhardt-Stift Wittenberg:Angiologie und Kardiologie

    WITHDRAWN

    Wittenberg, Germany

  • Evangelisches Krankenhaus Hubertus

    RECRUITING

    Berlin, Germany

  • General Intensive Care Unit, Hadassah Medical Organisation

    RECRUITING

    Jerusalem, Israel

  • ICU General Resuscitation (RES UP), General University hospital

    RECRUITING

    Prague, Czechia

  • ICU General Resuscitation (RES2)

    RECRUITING

    Prague, Czechia

  • ICU Metabolic, General University hospital

    RECRUITING

    Prague, Czechia

  • Johanna-Etienne Hospital Neuss, Interdisciplinary ICU

    RECRUITING

    Neuss, Germany

  • Medical and Neurological Intensive Care Unit, University Hospital of Düsseldorf

    RECRUITING

    Düsseldorf, Germany

  • Neurosurgical and Traumatological ICU ZI13, University Hospital of Düsseldorf

    RECRUITING

    Düsseldorf, Germany

  • S.C. Anestesia - Rianimazione Azienda Ospedaliera Santa Maria - Terni

    WITHDRAWN

    Terni, Italy

  • S.C. Anestesia e Rianimazione 1 - Terapia Intensiva Cardiochirurgica, Azienda Ospedaliera Universitaria S. Maria della Misericordia

    WITHDRAWN

    Perugia, Italy

  • S.C. Anestesia e Rianimazione 2 - Terapia Intensiva, Azienda Ospedaliera Universitaria S. Maria della Misericordia

    RECRUITING

    Perugia, Italy

  • Surgical Intensive Care Unit CIA1/CIB1, University Hospital of Düsseldorf

    RECRUITING

    Düsseldorf, Germany

  • The Coronary Care Intensive Care Unit, Hadassah Hospital, Ein Kerem

    RECRUITING

    Jerusalem, Israel

  • The Neurosurgical Intensive Care Unit, Hadassah Hospital, Ein Kerem

    RECRUITING

    Jerusalem, Israel

  • UOC di Anestesia e Rianimazione Cardio Toraco Vascolare dell'AOU San Giovanni di Dio e Ruggi d'Aragona "Scuola Medica Salernitana", Salerno University Hospital

    RECRUITING

    Salerno, Italy

  • Unfallkrankenhaus Berlin

    WITHDRAWN

    Berlin, Germany

  • University Hospital of Larissa, Critical Care Department

    RECRUITING

    Larissa, Greece

  • Universitätsklinikum Halle (Saale): Klinik für Innere Medizin III

    RECRUITING

    Halle, Germany

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