Can tiny needles tame your knee pain?
NCT ID NCT02890485
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether dry needling can ease knee pain and improve leg strength and function in people with patellofemoral pain syndrome (pain around the kneecap). Researchers will give dry needling treatments to 120 adults aged 18 to 40 and measure changes in pain and movement over three weeks. The goal is to see if this needle technique helps muscles relax and reduces discomfort.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2016
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18-40 years-of-age * Referred for physical therapy * Presence of anterior knee pain around the patella during ascending/descending stairs, squatting, and/or running for at least 3 months. Exclusion Criteria: * Unable to provide consent * Bilateral patellofemoral pain syndrome * Received previous dry needling treatments * Pregnancy * History of pain less than 3 months * Imaging demonstrating the presence of confounding internal abnormality (e.g. chondral defects, ligamentous injury, and/or meniscal pathology), * Patellar instability * Presence of a neurological condition that would affect movement * Contraindications to dry needling techniques (e.g. a history of bleeding disorders, phobia of needles, an active cancer diagnosis, and presence of other systemic illness such as fever or signs of infection) * Actively receiving treatment for knee pain outside of the current study protocol while enrolled in the study; * received active and supervised PT treatment for knee pain within the last 4 weeks; * history of knee surgery less than 6 months ago * history of surgical correction of the patellofemoral complex (e.g. MPFL reconstruction, patellar realignment surgery, etc)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The Ohio State University Wexner Medical Center
RECRUITINGColumbus, Ohio, 43221, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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