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Could a simple pill replace the shot for syphilis?

NCT ID NCT04838717

First seen Nov 20, 2025 · Last updated May 23, 2026 · Updated 24 times

Summary

This study tested whether a 14-day course of doxycycline pills works as well as the standard penicillin shot for curing early syphilis. About 200 adults with early-stage syphilis took part. The goal is to offer a reliable oral option, especially when penicillin is in short supply.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHRU Jean Minjoz

    Besançon, 25000, France

  • CHU Toulouse - Hôpital de la Grave - GeGIDD

    Toulouse, 34000, France

  • Hôpital Henri Mondor

    Créteil, 94000, France

  • Hôpital Hotel Dieu

    Paris, 75001, France

  • Hôpital Saint Louis - GeGIDD

    Paris, 75009, France

  • Hôpital Saint Louis - SMIT

    Paris, 75009, France

  • Hôpital de la Croix Rousse

    Lyon, 69000, France

Conditions

Explore the condition pages connected to this study.