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Could a simple pill replace the shot for syphilis?

NCT ID NCT04958122

First seen May 09, 2026 · Last updated May 23, 2026 · Updated 2 times

Summary

This study compares two antibiotics—cefixime (a pill) and penicillin G (a shot)—for treating early syphilis in 400 adults, including those with well-controlled HIV. The goal is to see if the pill works as well as the standard shot. Participants must have a positive blood test and be at least 18 years old.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Southern California

    RECRUITING

    Los Angeles, California, 90032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.