Could a simple pill replace the shot for syphilis?
NCT ID NCT04838717
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a 14-day course of doxycycline pills works as well as the standard penicillin shot for curing early syphilis. About 200 adults with early-stage syphilis took part. The goal is to offer a reliable oral option, especially when penicillin is in short supply.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHRU Jean Minjoz
Besançon, 25000, France
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CHU Toulouse - Hôpital de la Grave - GeGIDD
Toulouse, 34000, France
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Hôpital Henri Mondor
Créteil, 94000, France
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Hôpital Hotel Dieu
Paris, 75001, France
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Hôpital Saint Louis - GeGIDD
Paris, 75009, France
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Hôpital Saint Louis - SMIT
Paris, 75009, France
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Hôpital de la Croix Rousse
Lyon, 69000, France