Could a simple pill replace the shot for syphilis?

NCT ID NCT04838717

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a 14-day course of doxycycline pills works as well as the standard penicillin shot for curing early syphilis. About 200 adults with early-stage syphilis took part. The goal is to offer a reliable oral option, especially when penicillin is in short supply.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHRU Jean Minjoz

    Besançon, 25000, France

  • CHU Toulouse - Hôpital de la Grave - GeGIDD

    Toulouse, 34000, France

  • Hôpital Henri Mondor

    Créteil, 94000, France

  • Hôpital Hotel Dieu

    Paris, 75001, France

  • Hôpital Saint Louis - GeGIDD

    Paris, 75009, France

  • Hôpital Saint Louis - SMIT

    Paris, 75009, France

  • Hôpital de la Croix Rousse

    Lyon, 69000, France

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