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Promising drug trial for hand and foot blisters halted early

NCT ID NCT05710185

First seen Jan 04, 2026 · Last updated May 19, 2026 · Updated 16 times

Summary

This study tested a daily pill called deucravacitinib for people with palmoplantar pustulosis, a chronic skin condition causing painful blisters on the palms and soles. Only 3 adults with moderate-to-severe disease were enrolled before the trial was stopped early. The goal was to see if the drug could reduce skin redness, blisters, and scaling by at least 50% after 24 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.