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Which filling base lasts longest? a Head-to-Head test

NCT ID NCT07762651

Disease control Sponsor: Tanta University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This trial tests five different materials placed beneath composite fillings in back teeth to see which one best supports the filling and keeps it firmly attached. Adults needing a standard back-tooth filling will receive one of the five materials at random. Dentists will check the fillings over 18 months to see how well each material holds up, aiming to find the most reliable option for everyday dental care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dentin replacement materials (Biodentine, ACTIVA BioACTIVE, glass ionomer cement)
What this could lead to
If one material proves superior, it could lead to longer-lasting, more durable tooth fillings for cavities, reducing the need for re-treatment.
What could go wrong
This is a small, early-stage trial, so results may not apply to all patients. The materials could perform differently in real-world conditions, and long-term outcomes beyond 18 months are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who are medically able to undergo routine dental restorative treatment. * Patients willing and able to provide written informed consent. * Patients with adequate oral hygiene and periodontal health for participation in the study. * Patients requiring posterior Class I restorations Exclusion Criteria: * Patients with systemic conditions that contraindicate routine dental treatment. * Patients unable or unwilling to provide informed consent. * Patients with poor compliance or inability to attend scheduled follow-up visits. * Teeth with clinical or radiographic evidence of irreversible pulpitis, pulp necrosis, or periapical pathology.

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Composite resins Composite restoration Dental caries

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Dentistry, Tanta University

    Tanta, Tanta, 31527, Egypt

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