Faster heart attack diagnosis put to the test in 28,000-Person trial
NCT ID NCT07727135
First seen Jul 27, 2026 · Last updated Aug 07, 2026 · Updated 3 times
Summary
This trial compares two blood-test strategies for diagnosing heart attacks in people with chest pain: the standard approach of testing at arrival and again 3 hours later, versus an accelerated approach testing at arrival and again after just 1 hour. The goal is to see whether the faster method is as safe while allowing patients to leave the hospital sooner. The study involves 28,000 adults at hospitals across Denmark.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- high-sensitivity cardiac troponin blood test
- What this could lead to
- If the 1-hour strategy proves safe, it could allow faster diagnosis and shorter hospital stays for millions of people with chest pain.
- What could go wrong
- The 1-hour test might miss some heart attacks that the 3-hour test would catch, potentially increasing risk after discharge.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 28,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults (≥18 years) presenting with suspected acute coronary syndrome (ACS) with a clinical indication for high-sensitivity cardiac troponin testing Exclusion Criteria: * Age \<18 years. * ST-segment elevation myocardial infarction (STEMI) identified on the presenting electrocardiogram and requiring immediate reperfusion therapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
11 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Aalborg University Hospital
Aalborg, 9000, Denmark
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Amager & Hvidovre Hospital
Hvidovre, 2650, Denmark
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Bispebjerg & Frederiksberg Hospital
Bispebjerg, 2400, Denmark
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Central Jutland Regional Hospital (Viborg Hospital & Silkeborg Hospital)
Viborg, 8800, Denmark
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Esbjerg og Grindsted Sygehus
Esbjerg, 6700, Denmark
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Gødstrup Regional Hospital
Gødstrup, 7400, Denmark
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Herlev & Gentofte Hospital
Herlev, 2730, Denmark
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Nordsjællands Hospital
Hillerød, 3400, Denmark
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Nykøbing Falster County Hospital
Nykøbing Falster, 4800, Denmark
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Odense University Hospital
Odense, 5000, Denmark
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Svendborg Hospital
Svendborg, 5700, Denmark
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Other studies related to the condition(s) this trial covers.
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