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Nerve block combo may ease chronic pain condition

NCT ID NCT04767646

Symptom relief Sponsor: Pôle Saint Hélier Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at whether giving a continuous nerve block along with intensive physical and occupational therapy can improve recovery in people with Complex Regional Pain Syndrome type 1 (CRPS 1). The study enrolled 30 patients and followed them for up to a year. The main goal was to see if starting this treatment earlier leads to better results.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
continuous peripheral nerve block (CPNB) plus intensive rehabilitation program
What this could lead to
If successful, this could point toward a more effective treatment strategy for CRPS type 1, especially if started earlier in the disease course.
What could go wrong
This is a small, completed study with only 30 participants and no control group, so results may not be generalizable. The nerve block procedure carries risks like infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Feb 2021

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * informed consent signed * Diagnosis of CRPS type 1 according to BUDAPEST criteria to the upper or lower limb * Affiliated to a social security scheme (beneficiary or entitled person) * Patients justifying the installation of a Continuous Peripheral Nerve Block (CPNB) including pain rebellious to physical and medicinal treatments, the presence of fixed dystonia, or kinesiphobia or who are no longer progressing in the rehabilitation algorithm and requiring the need for a specialised technical platform. Exclusion Criteria: * CRPS Type 2 * Contra-indication to the analgesics used (bupivacaine, ropivacaine, levobupivacaine) * Severe psychiatric decompensation * Under legal protection measures * Pregnant women

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Conditions

The condition(s) this trial relates to.

complex regional pain syndrome complex regional pain syndrome type 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRPS (complex regional pain syndrome) type I

Contacts and locations

Locations

  • Pôle Saint Hélier

    Rennes, Brittany Region, 35000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.