Could early use of a 'Smart' stimulator tame CRPS pain?
NCT ID NCT06421350
First seen Nov 03, 2025 · Last updated Jun 23, 2026 · Updated 36 times
Summary
This study tests whether using a closed-loop spinal cord stimulator early in complex regional pain syndrome (CRPS) works better than waiting until the chronic phase. The device automatically adjusts its settings based on the body's signals. Researchers will enroll 32 adults with CRPS and track changes in pain severity, stimulation levels, and a blood marker of pain over 6 months.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Scripps Clinic Torrey Pines
RECRUITINGLa Jolla, California, 92037, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Closed-loop spinal cord stimulation device
What this could lead to
If it works, this could show that treating CRPS early with a smart spinal cord stimulator provides better pain relief and may slow disease progression.
What could go wrong
This is a small early-stage study with only 32 people, so results may not apply to everyone. The device requires surgery and carries risks like infection or lead movement.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.