Could early use of a 'Smart' stimulator tame CRPS pain?
NCT ID NCT06421350
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether using a closed-loop spinal cord stimulator early in complex regional pain syndrome (CRPS) works better than waiting until the chronic phase. The device automatically adjusts its settings based on the body's signals. Researchers will enroll 32 adults with CRPS and track changes in pain severity, stimulation levels, and a blood marker of pain over 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Closed-loop spinal cord stimulation device
- What this could lead to
- If it works, this could show that treating CRPS early with a smart spinal cord stimulator provides better pain relief and may slow disease progression.
- What could go wrong
- This is a small early-stage study with only 32 people, so results may not apply to everyone. The device requires surgery and carries risks like infection or lead movement.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Scripps Clinic Torrey Pines
RECRUITINGLa Jolla, California, 92037, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Nerve block combo may ease chronic pain condition