Pain drug lyrica put to the test for rare limb condition – but trial stalls
NCT ID NCT00891397
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding pregabalin (Lyrica) to standard treatment could reduce pain and improve function in people with complex regional pain syndrome (CRPS) of the upper limb. Only 14 adults were enrolled before the trial was stopped early. The goal was to see if the drug provided meaningful pain relief compared to a placebo sugar pill.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pregabalin (Lyrica)
What this could lead to
If it worked, this could point toward a way to reduce pain and improve hand/arm function for people with complex regional pain syndrome.
What could go wrong
The trial was terminated early and only enrolled 14 people, so results are very limited. It is unclear if pregabalin offers real benefit over placebo for this condition.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hamilton General Hospital
Hamilton, Ontario, L8L 2X2, Canada