Pain drug lyrica put to the test for rare limb condition – but trial stalls
NCT ID NCT00891397
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding pregabalin (Lyrica) to standard treatment could reduce pain and improve function in people with complex regional pain syndrome (CRPS) of the upper limb. Only 14 adults were enrolled before the trial was stopped early. The goal was to see if the drug provided meaningful pain relief compared to a placebo sugar pill.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Pregabalin (Lyrica)
- What this could lead to
- If it worked, this could point toward a way to reduce pain and improve hand/arm function for people with complex regional pain syndrome.
- What could go wrong
- The trial was terminated early and only enrolled 14 people, so results are very limited. It is unclear if pregabalin offers real benefit over placebo for this condition.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hamilton General Hospital
Hamilton, Ontario, L8L 2X2, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a smart brain implant outsmart chronic pain?
- Could a Nerve-Zapping ear device ease chronic pain?
- Magnetic pulses to the brain aim to quiet CRPS pain
- Teens with chronic pain try dance as medicine
- Brain scans aim to unlock secrets of chronic pain in kids
- Apple watch study to track CRPS pain triggers in kids cancelled