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Can a heart scan save lives in rheumatoid arthritis? major study aims to find out

NCT ID NCT07363980

Knowledge-focused Sponsor: Ellen Margrethe Hauge Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will use advanced heart scans (coronary CT angiography) on 4,000 people with rheumatoid arthritis aged 50-75. The goal is to better understand why people with this condition have higher risks of heart attacks, strokes, and lung problems. Researchers will track participants for up to 10 years to see how early signs of disease relate to future health events.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better ways to identify and manage heart and lung problems in people with rheumatoid arthritis, potentially reducing heart attacks and strokes.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test a new drug or cure. The results may take years and might not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 4,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2024

Expected to finish

Dec 2040

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with rheumatoid arthritis from rheumatology outpatient clinics across Denmark.

Ages

50 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Fulfill the ACR/EULAR-2010 criteria for rheumatoid arthritis * Attending or has attended at least one visit during the last two years in rheumatology outpatient clinic for diagnostic or monitoring purposes related to rheumatoid arthritis * Age 50-75 years Exclusion Criteria: * Diagnosed with overlapping systemic autoimmune diseases other than secondary Sjogren's syndrome * Active cancer * Prior coronary atherosclerotic symptoms as defined by myocardial infraction, percutaneous coronary intervention, or coronary artery bypass grafting * Allergy to radiocontrast agents * Estimated glomerular filtration rate (eGFR) \< 30 mL/min * BMI \> 35 kg/m2 * Persistent atrial fibrillation

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Conditions

The condition(s) this trial relates to.

anxiety disorder atherosclerotic cardiovascular disease cardiovascular disorder chronic obstructive pulmonary disease COPD, severe early onset depressive disorder disease ischemic disease lung cancer lung disorder lung neoplasm Respiration Disorders rheumatoid arthritis rheumatoid arthritis-associated interstitial lung disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety disorders Atherosclerotic ischemic disease Cardiovascular (CV) risk Cardiovascular and respiratory disease Cardiovascular biomarkers Cardiovascular disease Cardiovascular disease (CKD) Cardiovascular disease (CVD) risk factors COPD (chronic obstructive pulmonary disease) Depressive and anxiety disorders Depressive disorder Interstitial lung disease in patients with rheumatoid arthritis Lung cancer (diagnosis) Pulmonary disease Pulmonary disease, chronic obstructive Pulmonary diseases or conditions Rheumatoid arthritis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus, Denmark

  • Esbjerg Hospital

    Esbjerg, Denmark

  • Regional Hospital Gødstrup

    Herning, Denmark

  • Silkeborg Regional Hospital

    Herning, Denmark

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