Triple-Drug attack shows promise for tough bladder cancer
NCT ID NCT04724018
First seen Nov 05, 2025 · Last updated Apr 30, 2026 · Updated 28 times
Summary
This study tests two antibody-drug conjugates (sacituzumab govitecan and enfortumab vedotin) with or without the immunotherapy pembrolizumab in people with metastatic urothelial cancer (bladder cancer that has spread). The first phase finds the safest dose, and the second phase checks how well the combination shrinks tumors. About 106 adults whose cancer has progressed after standard treatments are eligible.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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