Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Brain training with a virtual coach may fight chemo fog

NCT ID NCT06027632

Symptom relief Sponsor: Centre Francois Baclesse Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether online cognitive exercises, guided by a neuropsychologist, can reduce memory and thinking problems (chemo brain) in 300 breast cancer patients after chemotherapy. Participants will do 20-minute brain games three times a week for 12 weeks, with some getting weekly video coaching. The goal is to see if the coaching helps more than doing the exercises alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
computerized cognitive stimulation program (HAPPYneuron-Pro)
What this could lead to
If it works, this could offer a practical, at-home way to reduce 'chemo brain' and improve daily thinking skills for breast cancer survivors.
What could go wrong
This is an early-stage study with no prior results for this specific supervised approach. The benefit may be small or no better than unsupervised exercises, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2024

Expected to finish

Mar 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 months and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient diagnosed with localized breast cancer * Age 18 or older, * Who have received adjuvant or neo-adjuvant chemotherapy and are currently undergoing adjuvant radiotherapy (ongoing hormone therapy, maintenance therapy other as target therapies or immunotherapy are permitted) until 6 months after end of radiotherapy. * Patients who report cognitive complaints that significantly impact their quality of life, as evaluated by the quality of life subscale of the FACT-Cog questionnaire. This subscale is composed by 4 questions: 1. I have been upset about these problems; 2. These problems have interfered with my ability to work; 3. These problems have interfered with my ability to do things I enjoy; 4. These problems have interfered with the quality of my life. Patients are eligible if their score on this subscale is at or below the 10th percentile, based on age guidelines and normative data (Lange et al., 2015), namely: * ≤ 8 for patients aged 30-49 years * ≤ 9 for patients aged 50-69 years * ≤ 10 for patients aged 70-89 years * Patients who have completed at least three years of primary school education, as determined by the Barbizet scale, * Patient with access to a functional laptop/computer with a keyboard, internet connection and an e-mail account - being able to use those tools alone, * Fluent in French, * Patients who have provided informed consent to participate in the study. Exclusion Criteria: * Personality disorder or any known progressive psychiatric pathology (e.g. schizophrenia), * Previous neurological history with ongoing cognitive symptoms (sequelae of head trauma, stroke, multiple sclerosis, epilepsy, neurodegenerative pathology, etc.), * Excessive alcohol intake or drug use, which could compromise participation to the intervention * Major visual and/or hearing deficit, * Patient who might not be able to complete neuropsychological testing, (including those with significant cognitive disorders that impede the completion of cognition tests, as determined by the cognitive screening test MoCA (MONTREAL COGNITIVE ASSESSMENT) and based on age and educational level according to GRECOGVASC (Reflection Group for Vascular COGnitive Assessment) normative data) * Already participating in a cognitive training program, * Refusal to participate, * Patient deprived of liberty or under guardianship, * Patient who might not be able to participate due to geographic, social or psychopathological reasons.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Breast cancer are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm cognitive disorder Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Cognitive dysfunction

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    25 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CH Métropole Savoie

    RECRUITING

    Chambéry, France

  • CHU de Limoges

    RECRUITING

    Limoges, France

  • CHU de Nimes

    RECRUITING

    Nîmes, France

  • Centre Antoine Lacassagne

    RECRUITING

    Nice, France

  • Centre Arrmoricain d'Oncologie

    NOT_YET_RECRUITING

    Plérin, France

  • Centre Eugène Marquis

    RECRUITING

    Rennes, France

  • Centre François Baclesse

    RECRUITING

    Caen, 14000, France

  • Centre George François Leclerc

    NOT_YET_RECRUITING

    Dijon, France

  • Centre Henri Becquerel

    RECRUITING

    Rouen, France

  • Centre Jean Perrin

    NOT_YET_RECRUITING

    Clermont-Ferrand, France

  • Centre Léon Bérard

    RECRUITING

    Lyon, France

  • Centre hospitalier de Bligny

    RECRUITING

    Briis-sous-Forges, France

  • Centre hospitalier de Pau

    RECRUITING

    Pau, France

  • Clinique Haute Energie

    NOT_YET_RECRUITING

    Nice, France

  • Clinique Mathilde

    RECRUITING

    Rouen, France

  • Clinique Medico-chirurgicale Charcot

    NOT_YET_RECRUITING

    Sainte-Foy-lès-Lyon, France

  • Groupe Hospitalier Mutualiste de Grenoble

    RECRUITING

    Grenoble, France

  • Gustave Roussy

    RECRUITING

    Villejuif, France

  • Hôpital Saint-Louis

    NOT_YET_RECRUITING

    Paris, France

  • Hôpital privé du Confluent

    RECRUITING

    Nantes, France

  • ICM Val d'Aurelle

    RECRUITING

    Montpellier, France

  • Institut Paoli Calmettes

    RECRUITING

    Marseille, France

  • Institut de Cancérologie de Lorraine

    NOT_YET_RECRUITING

    Nancy, France

  • La Pitié Salpétrière

    NOT_YET_RECRUITING

    Paris, France

  • Polyclinique Bordeaux Nord Aquitaine

    NOT_YET_RECRUITING

    Bordeaux, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.