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Brain training game tested for anxiety, depression, and PTSD

NCT ID NCT06273527

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 27 times

Summary

This study tests a computer program called COGENT, designed to improve thinking skills like memory and attention in people with anxiety, depression, or PTSD. 128 adults will be randomly assigned to either the COGENT training or a sham program. Researchers will compare changes in cognitive performance and brain activity before and after the training.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UC San Diego

    RECRUITING

    San Diego, California, 92037, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

computer-based cognitive training program (COGENT)

What this could lead to

If it works, this could point toward a non-drug way to improve thinking and reduce repetitive negative thoughts in people with anxiety, depression, or PTSD.

What could go wrong

This is an early-stage study with only 128 participants, and the sham group may also show some improvement. The training is computer-based, so real-world benefits may be limited.

Conditions

The condition(s) this trial relates to.

anxiety disorder Depression post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.