Brain wave test may personalize thinking skills training for veterans
NCT ID NCT04395157
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a brain wave measurement called mismatch negativity (MMN) can help match veterans with mental illness to the most effective cognitive training program. 100 veterans with conditions like schizophrenia, PTSD, or mood disorders participated. The goal was to see if this approach improves thinking, daily function, and quality of life better than a one-size-fits-all method.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- computerized cognitive training exercises
- What this could lead to
- If successful, this could help personalize cognitive rehabilitation for veterans with mental illness, improving thinking skills and daily life.
- What could go wrong
- This is a small, completed study focused on matching people to treatment, not testing a new therapy. Results may not apply broadly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
100 people
The number who actually took part.
- Started
-
Dec 2020
- Finished
-
Apr 2025
- Lead sponsor
-
A government agency
The lead sponsor is a US federal agency other than the NIH.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Veterans are currently enrolled in or within 6 weeks of discharge from (as relevant): a VA San Diego Healthcare System (VASDHS) psychosocial rehabilitation and recovery center (PRRC), VASDHS mental health residential rehabilitation treatment program (RRTP), VASDHS acute inpatient hospitalization or VASDHS outpatient mental health treatment
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Veterans are currently enrolled in or within 6 weeks of discharge from (as relevant): a VA San Diego Healthcare System (VASDHS) psychosocial rehabilitation and recovery center (PRRC), VASDHS mental health residential rehabilitation treatment program (RRTP), VASDHS acute inpatient hospitalization or VASDHS outpatient mental health treatment * have a DSM-5 mental illness, including: * schizophrenia * schizoaffective disorder * delusional disorder * major depressive disorder * bipolar disorder * generalized anxiety disorder * PTSD * fluent and literate in English * no impairment in hearing or vision Exclusion Criteria: * active substance use within the last 30 days * positive urine drug screen conducted as part of the screening process * have acute/ongoing thoughts of self-harm or harming others * intellectual disability or a neurocognitive disorder (i.e. dementia)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
VA San Diego Healthcare System, San Diego, CA
San Diego, California, 92161-0002, United States
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