Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Does cannabis work differently for men and women? new study investigates

NCT ID NCT04385082

Knowledge-focused Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jul 07, 2026 · Updated 3 times

Summary

This study aims to understand if cannabis affects pain relief and the risk of abuse differently in men and women. Researchers will give 160 regular cannabis users either active cannabis or a placebo and measure their pain response, drug effects, and blood levels. The goal is to gather knowledge that could lead to safer, more personalized cannabis use.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Cannabis (THC)
What this could lead to
If successful, this could help personalize cannabis use for pain management based on sex, potentially improving safety and effectiveness.
What could go wrong
This is an early Phase 1 study focused on understanding differences, not proving a treatment works. Results may not lead to direct medical recommendations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

About 160 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2021

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or non-pregnant female aged 21-55 years * Report use of cannabis an average of 1-7 days per week * Not currently seeking treatment for their cannabis use * Urine test positive for recent cannabis use for heavy users * No reported adverse effects with cannabis smoking in light users * Have a Body Mass Index from 18.5 - 34kg/m2. * Able to perform all study procedures * FEMALES: Currently practicing a non-hormonal effective form of birth control * FEMALES: Must be regularly cycling Exclusion Criteria: * Meeting DSM-V criteria for any substance use disorder other than nicotine, caffeine, or cannabis use disorder * Report using other illicit drugs in the prior 4 weeks * History or current evidence of severe psychiatric illness or medical condition judged by the study physician and PI to put the participant at greater risk of experiencing adverse events due to completion of study procedures, interfere with their ability to participate in the study, or their capacity to provide informed consent. * Current use of medical cannabis, prescription analgesics, or any medications that may affect study outcomes * Current pain * Insensitivity to the cold water stimulus of the Cold Pressor Test * FEMALES: using a hormonal contraceptive

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Abuse, drug are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

cannabis dependence Pain substance abuse substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abuse, drug Pain

Contacts and locations

Locations

  • University of California, Los Angeles

    Los Angeles, California, 90095, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.