New tool aims to ease tough talks on cancer drug resistance
NCT ID NCT04118062
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study aimed to create a communication tool to help doctors and patients discuss when cancer stops responding to treatment. Researchers interviewed 128 people, including patients with certain breast cancers, metastatic uveal melanoma, parents of children with cancer, and healthcare experts. Through surveys and group discussions, they developed a booklet to guide these conversations and improve shared decision-making.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could create a practical booklet to improve how doctors and patients talk about treatment resistance, making these difficult conversations clearer and more supportive.
- What could go wrong
- This is a small, completed study focused on developing a tool, not testing a treatment. The tool may not work well in all settings or for all patients.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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128 people
The number who actually took part.
- Started
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Feb 2021
- Finished
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May 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients: 1. To be 18 years of age or older ; 2. To have metastatic uveal melanoma (MUM) or triple negative or luminal B breast cancer ; 3. To have received the information that the disease is resistant to treatment ; 4. To have read the information and signed the informed consent. * Parents of a sick child: 1. To be a parent (parental authority holder) of a child with cancer ; 2. To have received the information that the child disease is resistant to treatment ; 3. To have read the information and signed the informed consent. * Expert patients: 1. To be 18 years of age or older ; 2. To have had cancer (regardless the cancer site) ; 3. To participated to an expert patient training (fine knowledge of the illness, experience with the disease) ; 4. To have read the information and signed the informed consent. * Professionals: 1. To be an oncologist (medical oncologist, surgeon, radiotherapist, supportive care specialist) and/or to be a researcher in oncology (doctor, biologist, geneticist ...) ; 2. To have patients with a triple-negative or luminal B breast cancer or metastatic uveal melanoma which is resistant to anti-tumor treatments and/or to take part to a research on resistance to cancer treatment; 3. To have read the information and signed the informed consent. Exclusion Criteria: * Patients \& parents of a sick child: 1. To have difficulties in understanding the French language. 2. Have or have had cancer (criteria only for parents); 3. Pregnant woman, likely to be pregnant or breastfeeding (criteria only for patients). 4. Persons deprived of their liberty or under guardianship; 5. Impossibility of study requirements respect for geographical, social or psychological reasons. * Expert patients: 1. To have difficulties in understanding the French language ; 2. Currently being undergoing anti-tumor treatment. * Professionals: 1. To have difficulties in understanding the French language ; 2. Not to be confronted in professional practice with resistance to anti-tumor treatments.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Institut Curie
Paris, 75005, France
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