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New tool aims to ease tough talks on cancer drug resistance

NCT ID NCT04118062

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study aimed to create a communication tool to help doctors and patients discuss when cancer stops responding to treatment. Researchers interviewed 128 people, including patients with certain breast cancers, metastatic uveal melanoma, parents of children with cancer, and healthcare experts. Through surveys and group discussions, they developed a booklet to guide these conversations and improve shared decision-making.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could create a practical booklet to improve how doctors and patients talk about treatment resistance, making these difficult conversations clearer and more supportive.
What could go wrong
This is a small, completed study focused on developing a tool, not testing a treatment. The tool may not work well in all settings or for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

128 people

The number who actually took part.

Started

Feb 2021

Finished

May 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients: 1. To be 18 years of age or older ; 2. To have metastatic uveal melanoma (MUM) or triple negative or luminal B breast cancer ; 3. To have received the information that the disease is resistant to treatment ; 4. To have read the information and signed the informed consent. * Parents of a sick child: 1. To be a parent (parental authority holder) of a child with cancer ; 2. To have received the information that the child disease is resistant to treatment ; 3. To have read the information and signed the informed consent. * Expert patients: 1. To be 18 years of age or older ; 2. To have had cancer (regardless the cancer site) ; 3. To participated to an expert patient training (fine knowledge of the illness, experience with the disease) ; 4. To have read the information and signed the informed consent. * Professionals: 1. To be an oncologist (medical oncologist, surgeon, radiotherapist, supportive care specialist) and/or to be a researcher in oncology (doctor, biologist, geneticist ...) ; 2. To have patients with a triple-negative or luminal B breast cancer or metastatic uveal melanoma which is resistant to anti-tumor treatments and/or to take part to a research on resistance to cancer treatment; 3. To have read the information and signed the informed consent. Exclusion Criteria: * Patients \& parents of a sick child: 1. To have difficulties in understanding the French language. 2. Have or have had cancer (criteria only for parents); 3. Pregnant woman, likely to be pregnant or breastfeeding (criteria only for patients). 4. Persons deprived of their liberty or under guardianship; 5. Impossibility of study requirements respect for geographical, social or psychological reasons. * Expert patients: 1. To have difficulties in understanding the French language ; 2. Currently being undergoing anti-tumor treatment. * Professionals: 1. To have difficulties in understanding the French language ; 2. Not to be confronted in professional practice with resistance to anti-tumor treatments.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institut Curie

    Paris, 75005, France

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