METASTATIC UVEAL MELANOMA
Clinical trials for METASTATIC UVEAL MELANOMA explained in plain language.
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New combo therapy targets liver tumors from eye cancer
Disease control Recruiting nowThis study tests whether combining the drug tebentafusp with a liver-directed radiation procedure (Y-90 radioembolization) can help control metastatic uveal melanoma that has spread to the liver. About 30 adults with this condition will receive the combination therapy. The goal i…
Matched conditions: METASTATIC UVEAL MELANOMA
Phase: PHASE2 • Sponsor: University of Miami • Aim: Disease control
Last updated May 26, 2026 04:21 UTC
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New pill shows promise for rare eye cancer that spreads
Disease control Recruiting nowThis study tests an experimental drug called NBM-BMX for people with metastatic uveal melanoma, a rare eye cancer that has spread to other parts of the body. The goal is to find the best dose, check for side effects, and see if the drug can shrink tumors or slow the cancer. About…
Matched conditions: METASTATIC UVEAL MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: Novelwise Pharmaceutical Corporation • Aim: Disease control
Last updated May 26, 2026 04:20 UTC
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Your own tumor cells could be the key to fighting advanced cancer
Disease control Recruiting nowThis early-phase trial tests a treatment made from your own immune cells (called tumor-infiltrating lymphocytes, or TILs) for advanced uveal melanoma, undifferentiated pleomorphic sarcoma, or dedifferentiated liposarcoma. About 30 participants will have their tumor removed, have …
Matched conditions: METASTATIC UVEAL MELANOMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 26, 2026 04:14 UTC
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New combo attack on rare eye cancer shows promise in early trial
Disease control Recruiting nowThis study tests a two-step treatment for people with a rare eye cancer (uveal melanoma) that has spread only to the liver. First, a chemotherapy drug is delivered directly to the liver through a special procedure. Then, a targeted immunotherapy drug is given to help the immune s…
Matched conditions: METASTATIC UVEAL MELANOMA
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New drug combo aims to shrink deadly eye cancer tumors
Disease control Recruiting nowThis study tests whether two drugs, cemiplimab and ziv-aflibercept, can shrink or stop the growth of metastatic uveal melanoma, a rare eye cancer that has spread to other parts of the body. About 32 adults with this condition will receive the combination treatment. The goal is to…
Matched conditions: METASTATIC UVEAL MELANOMA
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 19, 2026 12:01 UTC
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New hope for rare eye cancer: experimental combo takes on standard treatment
Disease control Recruiting nowThis study tests whether a new drug called RP2, given with nivolumab, works better than the standard combination of ipilimumab and nivolumab for people with metastatic uveal melanoma (a rare eye cancer that has spread). About 280 adults who have not had prior immunotherapy will r…
Matched conditions: METASTATIC UVEAL MELANOMA
Phase: PHASE2, PHASE3 • Sponsor: Replimune, Inc. • Aim: Disease control
Last updated May 18, 2026 12:03 UTC
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Spinal immunotherapy injection shows promise for tough brain cancers
Disease control Recruiting nowThis early-phase study tests a combination of two ways to give the immunotherapy drug nivolumab: through a vein and directly into the fluid around the spine. It is for people with melanoma or lung cancer that has spread to the lining of the brain or spinal cord (leptomeningeal di…
Matched conditions: METASTATIC UVEAL MELANOMA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New drug targets rare genetic cancers in early trial
Disease control Recruiting nowThis study tests a new drug called IDE196 in people with certain cancers that have specific gene mutations (GNAQ/11 or PRKC fusions), including metastatic uveal melanoma and colorectal cancer. The trial has two phases: first to find safe doses, then to see if the drug shrinks tum…
Matched conditions: METASTATIC UVEAL MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: IDEAYA Biosciences • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New combo therapy targets eye cancer in the liver
Disease control Recruiting nowThis study tests a drug called tebentafusp combined with treatments directed at the liver for people with a rare eye cancer (uveal melanoma) that has spread to the liver. About 109 adults with a specific genetic type (HLA-A*0201) will participate. The goal is to see if the combin…
Matched conditions: METASTATIC UVEAL MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated May 13, 2026 15:58 UTC