Can learning about pain boost exercise benefits for arthritic knees?
NCT ID NCT07565298
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tested whether adding group-based pain neuroscience education (PNE) to a community exercise program helps older women with knee osteoarthritis. Nineteen women aged 60+ were randomly assigned to 10 weeks of exercise plus PNE or exercise alone. Researchers measured daily function, pain, and knowledge about pain. The goal was to see if this combined approach is feasible and offers extra benefits.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- pain neuroscience education (PNE) plus exercise
- What this could lead to
- If it works, this approach could offer a simple, non-drug way to help older women with knee osteoarthritis feel better and move more easily.
- What could go wrong
- This was a very small pilot study with only 19 participants, so results may not apply to everyone. The added benefit of PNE over exercise alone is still uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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19 people
The number who actually took part.
- Started
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Aug 2024
- Finished
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Nov 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- Medical diagnosis of knee osteoarthritis with current knee pain. Exclusion Criteria: * Inability to understand study procedures during baseline assessment. Mini-Mental State Examination (MMSE) cutoff used to define adequate comprehension for study participation was ≥24/30). * Severe neurological disease. * Anticipated inability to attend all educational sessions or attendance less than 80% at the end of the program.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Pontificia Universidad Católica de Chile
Santiago, Chile
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