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Brain scans reveal why fatty foods repel anorexia patients

NCT ID NCT07344831

Knowledge-focused Sponsor: Centre Hospitalier Universitaire de Saint Etienne Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 17, 2026 · Updated 2 times

Summary

This study looks at how the brains of women with anorexia nervosa respond to fatty food smells and images. Researchers will use brain scans to compare their reactions to those of healthy women. The goal is to understand why fatty foods cause aversion, which could help improve future treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Dec 2026

An estimate. Start dates often move.

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Person affiliated or entitled to a social security scheme * Person having received informed information on the study and having co-signed, with the investigator, a consent to participate in the study * female person * Person affiliated or entitled to a social security scheme * Over 18 years'old * Knowing how to read and write French * Patient diagnosed with anorexia nervosa according to DSM-5 criteria for at least 5 years (HAS criteria). Failure of prior outpatient or/and hospitalization care over the last 12 months: stable or falling low BMI, unmodified food restriction, continued fear of weight gain, disturbances in the perception of body image * BMI \< 18.5 kg/m² for volunteers in a state of constitutional thinness. The absence of eating disorder and the absence of restriction to DEBQ questionnaires. Fertility preserved. * For volunteers of normal weight: 18.5 kg/m² \< BMI \< 25 kg/m² Exclusion Criteria: * Pregnant women, parturient, nursing mothers; * Persons deprived of their liberty, hospitalized without consent, hospitalized for purposes other than research; * Minors * Refusal of the study by the participant * Person incapable of giving informed consent * Artificial nutrition * Associated organic damage favoring undernutrition: other chronic diseases (digestive, infectious, endocrine, pulmonary, cardiac, neurological), neoplasms, etc. * Abuse of psychoactive substances except tobacco * Characterized depressive episode, psychosis * Score less than 14 on the Edinburgh laterality questionnaire. * Contraindications to MRI or allergy to one of the components of the olfactory and taste tests * Smokers * Smell or taste alterations

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Conditions

The condition(s) this trial relates to.

anorexia nervosa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anorexia nervosa

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • CHU de Saint-Etienne

    Saint-Etienne, 42055, France

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