New rehab approach aims to ease knee pain without drugs
NCT ID NCT07411027
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a special exercise program that focuses on body awareness and coordination for people with patellofemoral pain syndrome (pain around the kneecap). Sixty adults with knee pain for at least 3 months will be randomly assigned to either this new rehab or standard physiotherapy. Researchers will measure changes in pain behavior, movement quality, and mental well-being to see if the new approach is more effective.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- sensorimotor rehabilitation
- What this could lead to
- If it works, this could offer a new, non-drug therapy to reduce knee pain and improve movement and quality of life.
- What could go wrong
- This is a small, early-stage study with only 60 participants. Results may not apply to everyone, and the new therapy may not be better than standard exercises.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18-45 years. * Clinical diagnosis of patellofemoral pain syndrome with anterior or retropatellar knee pain. * Knee pain lasting for at least 3 months. * Pain intensity of at least moderate level during functional activities such as stair climbing, squatting, or prolonged sitting. * Ability to understand and follow instructions and provide informed consent. * Willingness to participate in the rehabilitation program. Exclusion Criteria: * History of knee surgery within the past 12 months. * Presence of other knee pathologies (e.g., ligament injury, meniscal tear, osteoarthritis). * Diagnosis of inflammatory or rheumatological diseases. * Neurological disorders affecting balance or movement. * Current pregnancy. * Participation in another structured physiotherapy or rehabilitation program within the past 3 months. * Any condition that may prevent safe participation in exercise.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Guneysu Physical Therspy and Rehabilitation School
Rize, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can an AI coach replace the Physio's touch for knee pain?
- Which exercise retrains the knee best? a Head-to-Head test
- Hip and foot moves may ease stubborn knee pain — a trial puts the theory to the test
- A simple hip exercise may boost knee pain recovery — trial puts it to the test