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Tight leg bands during workouts may unlock stem cell release

NCT ID NCT07213726

Knowledge-focused Sponsor: Andrews Research & Education Foundation Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether using a special tourniquet system to slow blood flow to the legs during exercise can increase the number of stem cells released into the bloodstream. Fifteen healthy adults aged 18 to 45 will do leg exercises with blood flow restriction, and researchers will measure stem cell levels before and after exercise. The goal is to understand how this technique affects the body's natural stem cell circulation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Delfi Personalized Tourniquet System (device to restrict blood flow during exercise)
What this could lead to
If successful, this could help researchers understand how to naturally boost stem cell circulation through exercise, potentially aiding recovery or healing.
What could go wrong
This is a very small, early observational study with only 15 healthy participants. It measures short-term changes, not long-term health benefits, so results may not apply to patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 15 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2022

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria 1. Volunteer population of healthy males and females aged 18-45. 2. Subjects consent to attending a total of 14 visits over a time span of seven to nine weeks. The breakdown of the 14 visits is as follows: 1 familiarization session, 12 experimental testing sessions, 1 final session. Exclusion Criteria Volunteers who have medical history involving one or more of the following medical conditions: 1. Diabetes 2. Uncontrolled hypertension 3. Autoimmune disorders 4. Blood disorders 5. Ongoing infectious disease 6. Cancer 7. Any disorder requiring immunosuppression treatment 8. Steroid usage 9. Significant cardiovascular, pulmonary, hepatic, or renal disease. 10. Volunteers where 20 minutes of intense exercise is contra-indicated will also be excluded from the study. 11. Positive pregnancy test

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood flow restriction (BFR) training effects Stem cell extraction after blood flow restriction BFR

Contacts and locations

Locations

  • Andrews Institute for Orthopaedics & Sports Medicine

    Gulf Breeze, Florida, 32561, United States

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