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Could a simple drug combo stop deadly liver bleeds?

NCT ID NCT07521332

First seen Apr 17, 2026 · Last updated May 24, 2026 · Updated 10 times

Summary

This study tests whether adding a blood thinner (apixaban) to a standard heart drug (carvedilol) can prevent serious complications like internal bleeding, fluid buildup, and liver failure in people with cirrhosis and high blood pressure in the liver. About 220 adults with stable cirrhosis will be randomly assigned to receive either the drug combo or a placebo plus carvedilol, and followed for one year. The goal is to see if this approach reduces hospitalizations and improves survival without causing dangerous bleeding.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asian Institute of Medical Sciences

    RECRUITING

    Hyderābād, Sindh, 71000, Pakistan

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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