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Could an arthritis drug ease depression in certain patients?

NCT ID NCT05415397

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 34 times

Summary

This study tests whether adding the anti-inflammatory drug celecoxib to standard depression treatment helps people with a specific type of depression linked to inflammation and energy-related symptoms like fatigue and weight gain. About 140 adults with this depression subtype will receive either celecoxib or a placebo for 12 weeks. The goal is to see if targeting inflammation improves depressive symptoms more than usual care alone.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Department of Psychiatry Amsterdam UMC

    Amsterdam, 1081 HJ, Netherlands

Conditions

Explore the condition pages connected to this study.