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Ankle test may flag kidney danger after heart surgery

NCT ID NCT07668830

Knowledge-focused Sponsor: Nanjing First Hospital, Nanjing Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 30, 2026 · Updated 3 times

Summary

This study looked at 516 patients who had surgery for a torn aorta (aortic dissection). Researchers checked if a high ankle-brachial index (a simple test of blood flow in the legs) before surgery was linked to kidney problems afterward. The goal was to see if this test could help predict acute kidney injury, but no treatment was given or tested.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify patients at higher risk for kidney injury after aortic dissection surgery, allowing for closer monitoring.
What could go wrong
This is a small, single-center, retrospective study, so results may not apply to all patients. It only looks for an association, not a cause.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

516 people

The number who actually took part.

Started

Jan 2021

Finished

Feb 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will include adult patients with acute Stanford type A aortic dissection who underwent surgical repair at Nanjing First Hospital, Nanjing Medical University, between January 2021 and February 2024. Eligible patients will be identified from existing hospital medical records. Patients will be included if preoperative ankle-brachial index data and perioperative renal function data are available.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients diagnosed with acute Stanford type A aortic dissection. 2. Patients who underwent surgical repair for acute Stanford type A aortic dissection at Nanjing First Hospital, Nanjing Medical University, between January 2021 and February 2024. 3. Patients aged 18 years or older. 4. Patients with available preoperative ankle-brachial index data. 5. Patients with available perioperative renal function data for assessment of postoperative renal outcomes. Exclusion Criteria: 1. Patients younger than 18 years. 2. Patients without available preoperative ankle-brachial index data. 3. Patients without sufficient perioperative serum creatinine data to assess postoperative acute kidney injury. 4. Patients with preoperative end-stage renal disease or maintenance dialysis. 5. Patients with incomplete key clinical data required for the main analysis.

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury cardiac surgery Aortic dissection type A

Contacts and locations

Locations

  • Nanjing First Hospital, Nanjing Medical University

    Nanjing, Jiangsu, 210006, China

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