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Blood vessel age may forecast kidney damage after heart surgery

NCT ID NCT07727772

Knowledge-focused Sponsor: Nanjing First Hospital, Nanjing Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This study looks at whether the biological age of a person's blood vessels, measured before heart surgery, can help predict their risk of acute kidney injury afterward. Researchers will assess vascular aging using noninvasive tests and routine lab results in about 470 adults undergoing cardiac surgery. The goal is to see if these markers can identify patients who might need closer monitoring or preventive steps after their operation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If vascular aging markers predict kidney injury, doctors could identify high-risk patients before surgery and tailor monitoring or preventive care.
What could go wrong
This is an observational study, not a treatment trial. It can only show associations, not cause and effect. Results may not apply to other hospitals or populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 472 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adult patients undergoing cardiac surgery at Nanjing First Hospital, Nanjing Medical University. Eligible patients will receive perioperative vascular aging assessment and postoperative renal function monitoring according to the study protocol. Participants will be followed for postoperative acute kidney injury within 7 days after surgery.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18 years or older. * Patients scheduled to undergo cardiac surgery at Nanjing First Hospital, Nanjing Medical University. * Patients who are able to provide written informed consent. * Patients who are expected to undergo perioperative vascular aging assessment and postoperative renal function monitoring according to the study protocol. Exclusion Criteria: * Patients younger than 18 years. * Patients with preoperative end-stage renal disease or maintenance dialysis. * Patients who are unable to complete the study-specified vascular aging assessment. * Patients who decline participation or withdraw informed consent.

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Conditions

The condition(s) this trial relates to.

acute kidney injury Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury cardiac surgery Postoperative complications Vascular aging

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Nanjing First Hospital, Nanjing Medical University

    Nanjing, Jiangsu, 210006, China

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