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COPD lungs may leak during exercise, study finds

NCT ID NCT06287476

Knowledge-focused Sponsor: Rigshospitalet, Denmark Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at whether people with COPD have abnormal leakage in their lung capillaries during exercise, which could contribute to shortness of breath. Researchers compared 32 participants (COPD patients and healthy controls) by measuring lung permeability before and after exercise. The goal was to understand the underlying mechanisms of breathlessness in COPD, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

May 2024

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria - individuals with COPD * Men and women * 45-80 years old * COPD (GOLD stage I to III) * Resting arterial oxygenation \> 90% Inclusion criteria - healthy controls * Men and women * 45-80 years old * Non-smokers * Normal lung function * Same sex, age (± 3 years) as the COPD group Exclusion criteria - individuals with COPD * Symptoms of ischemic heart disease * Known heart failure * Symptoms of illness, including fever, within 2 weeks prior to the study * Pregnancy * • Known renal or liver diseaseActive smoking (within 3 weeks) Exclusion criteria - healthy controls * Known chronic lung disease * Symptoms of ischemic heart disease * Known heart failure * Symptoms of illness, including fever, within 2 weeks prior to the study * Pregnancy * Known renal or liver disease * Active smoking (within 3 weeks)

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic obstructive pulmonary disease

Contacts and locations

Locations

  • Center For Physical Activity Research, Rigshospitalet

    Copenhagen, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.