New gel filler shows promise for wrinkle reduction
NCT ID NCT07618468
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a gel-like implant (Algeness) to improve the look of wrinkles and other skin contour problems. 40 adults aged 30-65 with age-related skin changes took part. The main goal was to see if the implant reduced wrinkle severity on a standard scale. The study is complete, and results showed a meaningful improvement.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Jun 2024
- Finished
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Apr 2025
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 30 and 65 years inclusive * Presence of signs of age-related facial skin changes (decreased turgor, elasticity, fine wrinkles, contour defects) * Signed informed voluntary consent * Willingness and ability to comply with study procedures and attend all scheduled visits Exclusion Criteria: * Age under 18 years * Individual intolerance or allergy to any component of the investigational device * Diagnosed tendency to keloid or hypertrophic scarring * Severe chronic diseases in the acute phase * Acute forms of dermatological diseases * Coagulation disorders * Treatment with medications affecting blood coagulation * Inflammatory or infectious processes in the injection zones * Diagnosed autoimmune pathologies * Pregnancy and lactation period * Filler injections in the same area within the past 12 months * Laser procedures or chemical peels within the past 3 months * Oncological diseases in history or at the time of inclusion * Participation in another clinical study within the past 3 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Estelab Clinic (Clinical Base of FSBEI FPE Russian Medical Academy of Continuing Professional Education)
Moscow, 119034, Russia
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Other studies related to the condition(s) this trial covers.
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