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Own-Blood gel may ease pain after wisdom tooth removal

NCT ID NCT07153133

Symptom relief Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a gel made from a patient's own blood (albumin platelet-rich fibrin) can reduce pain, swelling, and improve healing after removing impacted wisdom teeth. Sixteen healthy adults had both lower wisdom teeth removed; one socket received the gel and the other did not. Researchers measured swelling, pain, wound healing, and blood markers of inflammation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
albumin platelet-rich fibrin gel (made from the patient's own blood)
What this could lead to
If it works, this could offer a simple, natural way to reduce pain and swelling after wisdom tooth removal.
What could go wrong
This is a very small, early study with only 16 people, so results may not apply to everyone. The gel is made from the patient's own blood, so risks are low but unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

16 people

The number who actually took part.

Started

Sep 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy patients classified as ASA (American Society of Anesthesiologists) Physical Status Classification Class I. * Patients seeking extraction of both mandibular third molars. * Patients aged 18 - 40 years old by the day of surgery. * Patients willing to participate in the study and commit to regular follow-up appointments. Exclusion Criteria: * Heavy Smokers (more than 25 cigarettes per day). * Patients with Poor oral hygiene. * Patients with history of a chemotherapy or radiotherapy

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tooth extraction site healing

Contacts and locations

Locations

  • Faculty of Dentistry, Mansoura Universty

    Al Mansurah, Egypt

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