New bone graft aims to save jawbone after tooth loss
NCT ID NCT07638358
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests Neobone®, a bone graft material, to see if it helps preserve the jawbone after a tooth is pulled. Thirty adults who need a tooth extraction will either receive the graft or let the socket heal naturally. Researchers will use 3D scans to measure bone volume changes over six months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Neobone® (Biphasic Calcium Phosphate) - a bone graft material
- What this could lead to
- If it works, this could offer a safe way to preserve jawbone shape after tooth removal, making future dental implants easier.
- What could go wrong
- This is a very early, small trial with only 30 people. The bone graft may not improve healing over natural recovery, and results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18 years or older * Acceptance of informed consent * Type 1 or 2 extraction sockets (Elian et al. 2007) Exclusion Criteria: * Presence of active infection or severe inflammation in the intervention zone * Relevant medical history that contraindicates implant surgery * Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score \>15%) and lack of motivation * Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%) * Uncontrolled and /or untreated periodontal disease * Heavy smokers (more than 10 cigarettes per day) * Immunosuppression
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Clinica Dentária Egas Moniz
RECRUITINGCaparica, Monte Da Caparica, 2829-511, Portugal
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Sticky bone vs chitosan: which graft better saves the jaw ridge after tooth extraction?
- Your pulled tooth could rebuild your jaw
- The race to save jawbone: four socket techniques go head to head
- Can a gel help save jawbone for better dental implants?
- New bone putty aims to save your jaw after a tooth pull
- Tooth extraction bone loss: which method saves the most jawbone?