Tooth extraction bone loss: which method saves the most jawbone?

NCT ID NCT07608289

Disease control Sponsor: University of Ostrava Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

After a tooth is pulled, the jawbone can shrink significantly, making it harder to place dental implants later. This study compares four common techniques to preserve bone: letting it heal naturally, using a collagen sponge, using a synthetic bone material, or using the patient's own tooth root (dentin). Researchers will measure bone width before and six months after extraction using 3D X-rays. The goal is to find which method best maintains bone volume for future dental work.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: autogenous dentin, collagen sponge, tricalcium phosphate
What this could lead to: If successful, this could identify the best technique to preserve jawbone after tooth extraction, making future dental implants easier and more successful.
What could go wrong: This is a small, early-stage study with only 80 participants, so results may not apply to everyone. The methods being tested are already in use, so no major breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18-70 years * no active periodontitis * signed informed consent with participation in the study * need for extraction of teeth other than third molars * patients requesting only standard/reimbursed care Exclusion Criteria: * drug or alcohol abuse * ongoing chemotherapy * ongoing radiotherapy * pregnancy * ongoing treatment of osteoporosis or other biological treatment with MRONJ risk * low compliance * patients asking for premium care

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tooth extraction site healing

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

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Tooth extraction bone loss: which method saves the most jawbone?

What the study statuses mean