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AI app could replace physiotherapist for knee pain relief

NCT ID NCT05173064

Symptom relief Sponsor: The University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether an AI-powered app can guide people with knee osteoarthritis through exercises at home, reducing pain and improving function as well as in-person physiotherapy. About 176 adults aged 50 and older with knee pain will be split into two groups: one receiving standard face-to-face physiotherapy, and the other using the AI app after an initial session. The goal is to see if the app can offer a cheaper, more accessible way to manage knee OA symptoms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
AI-powered exercise app (Technological Surrogate Physiotherapist)
What this could lead to
If successful, this could provide a convenient, low-cost alternative to in-person physiotherapy for managing knee osteoarthritis pain and function.
What could go wrong
This is a relatively small, early-stage trial (176 participants) comparing an app to standard care. The AI may not match the benefits of hands-on therapy, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 176 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: 1. At least 50 years of age; 2. Report having knee pain most days of the week; 3. Has radiographic evidence of grade 2, 3, or 4 knee OA on the K-L scale in the posteroanterior and/or skyline view in at least 1 knee; 4. Willing and able, both physically and cognitively, to perform the exercises required in the study protocol; 5. Has normal or corrected-to-normal vision; 6. Able to speak Cantonese and read Chinese, AND 7. Able to provide written informed consent. Exclusion criteria: 1. Having a history of knee or hip replacement surgery; 2. Being nonambulatory; 3. Having systemic inflammatory arthritis (e.g., gout); 4. Having a history of trauma (e.g., fractures around the knee, dislocation, sprains or tears of soft tissues like ligaments) or surgical arthroscopy of either knee within the past 6 months; 5. Having intra-articular injection to the knee within the past 6 months; 6. Having cognitive impairment; 7. Involvement in a similar study (i.e., involving physical exercise or physical therapies for knee pain) within the past 6 months; 8. Undergoing recent or imminent surgery (within 3 months) , OR 9. Having medical co-morbidities that preclude participation in exercise.

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Conditions

The condition(s) this trial relates to.

Motor Activity osteoarthritis, knee Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis Pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • 826, Haking Wong Building, Pokfulam, The University of Hong Kong, Hong Kong

    Hong Kong, 000, Hong Kong

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