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AI learns from thousands of ICU patients to improve ventilator care

NCT ID NCT05668637

Knowledge-focused Sponsor: Technische Universität Dresden Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at past treatment data from over 300,000 ICU patients who needed a breathing machine (ventilator). The goal is to train an artificial intelligence (AI) system to help doctors choose the safest ventilator settings. By learning from real-life decisions and patient responses, the AI may reduce the risk of lung damage. No new treatments are given; the study only analyzes existing records.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 318,542 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2023

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Intensive care patients receiving invasive mechanical ventilation

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: • Subjects who are 18 years or older and receive invasive mechanical ventilation for \> 4 hours Exclusion Criteria: • Patients receiving one-lung ventilation

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Conditions

The condition(s) this trial relates to.

Ventilator-Induced Lung Injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Invasive mechanical ventilation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites in 2 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Better Care Sl

    ACTIVE_NOT_RECRUITING

    Sabadell, Spain

  • Cleveland Clinic Foundation, Cleveland, USA

    RECRUITING

    Cleveland, Ohio, 44195, United States

  • Fundacio Parc Tauli

    COMPLETED

    Sabadell, Spain

  • Fundacion Publica Andaluza Progreso Y Salud

    ACTIVE_NOT_RECRUITING

    Seville, Spain

  • Inselspital, Universitätsspital Bern

    COMPLETED

    Bern, Switzerland

  • Institut Fur Angewandte Informatik (Infai) Ev

    ACTIVE_NOT_RECRUITING

    Leipzig, Germany

  • Institut Mihajlo Pupin

    ACTIVE_NOT_RECRUITING

    Belgrade, Serbia

  • University Hospital Carl Gustav Carus Dresden

    RECRUITING

    Dresden, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.