Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New sedative may offer safer sleep for ICU patients

NCT ID NCT06261996

Symptom relief Sponsor: Henan Provincial People's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested fospropofol against the standard sedative propofol in 200 adults on breathing machines in the ICU. Researchers measured how well each drug kept patients calm and tracked side effects like low blood pressure and injection pain. The goal was to see if fospropofol could be a safer or more effective option for sedation during mechanical ventilation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
fospropofol
What this could lead to
If fospropofol proves safer or more effective than propofol, it could become a preferred sedative for ICU patients on breathing machines.
What could go wrong
This is a small, early-stage study with only 200 participants. Results may not apply to all ICU patients, and side effects like low blood pressure or slow heart rate are possible with both drugs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

200 people

The number who actually took part.

Started

Apr 2024

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Aged 18-75 years old 2. Intubation and mechanical ventilation \<12h before enrollment 3. Expected to require continuous invasive ventilation and sedation less than 6h after admission to anesthesia intensive care unit (AICU). 4. Signed informed consent Exclusion Criteria: 1. parturient, childbirth or lactating mothers 2. acute severe neurological disease or coma 3. chronic renal failure 4. previous mechanical ventilation \>12h 5. severe liver dysfunction (Child-Pugh score C) 6. BMI \>30kg/m2 (\>90kg) 7. dying

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Invasive mechanical ventilation are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Invasive mechanical ventilation

Contacts and locations

Locations

  • Henan Provincial People's Hospital

    Zhengzhou, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.