Can AI help keep your mind sharp? new trial tests digital coach for memory decline
NCT ID NCT07474038
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a 12-month program combining telehealth sessions with daily AI-guided brain exercises can help older adults with mild cognitive impairment (MCI) maintain or improve their memory and thinking skills. 130 participants will be randomly assigned to either the AI program or usual care. The main goal is to see if the AI group shows better cognitive scores after 6 months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- AI-supported cognitive rehabilitation program
- What this could lead to
- If it works, this could offer a practical, home-based way to slow cognitive decline and improve daily function in people with mild cognitive impairment.
- What could go wrong
- This is a relatively small, early-stage trial (130 participants) testing a behavioral intervention, not a drug. Results may not apply to everyone, and the AI component may not add significant benefit over usual care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 130 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Mar 2026
- Expected to finish
-
Dec 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
65 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 65 years or older * Diagnosis of mild cognitive impairment (MCI) * Montreal Cognitive Assessment (MoCA)-BLIND adjusted score (13-18) * Able to provide informed consent * English fluency sufficient to complete study assessments and participate in intervention sessions * Access to and ability to use a computer or mobile device with internet connectivity Exclusion Criteria: * Current receipt of ongoing behavioral health treatment or psychotherapy from a Kaiser Permanente clinician * Diagnosis of bipolar disorder, schizophrenia spectrum disorder, or other serious mental illness that would interfere with participation * Significant communication impairment that would prevent participation in conversational or telehealth sessions
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Mild cognitive impairment (MCI) are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Kaiser Permanente Southern California
Pasadena, California, 91101, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Zapping the brain to sharpen mind and stride
- Zapping the brain at 10 hz may help older adults stay steady
- Robot arm meets virtual reality to train the Parkinson's brain
- Three brain tests combined in one study to spot dementia earlier
- A brain zapping and tai chi combo may slow memory decline
- Can a dead probiotic revive aging brains?