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Scientists launch biobank to uncover genetic secrets of AF and stroke

NCT ID NCT03611816

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is creating a biological bank of blood samples from 1,000 people with atrial fibrillation (AF) and stroke. Researchers will collect DNA and plasma to study the genetic roots of these conditions. The goal is to better understand why AF leads to stroke and find new drug targets. Participants provide blood samples and clinical data, but no experimental treatment is given.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this biobank could help researchers discover genetic causes of atrial fibrillation and stroke, potentially pointing toward new treatments.
What could go wrong
This is an observational biobank study, not a treatment trial. It will not directly benefit participants and may not lead to any new therapies for years.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2018

Expected to finish

Apr 2033

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Atrial fibrillation patient Stroke patient Patient over 80

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Group 1a * Inclusion Criteria : \- AF history * Exclusion Criteria : * No AF history * patient who didn't signed consent Group 1b * Inclusion Criteria : * AF history * Scheduled electrophysiological exploration or AF ablation * Exclusion Criteria : * No AF history * pregnant women * patient who didn't signed consent Group 1c * Inclusion Criteria : * AF/AT history * Stroke history * Exclusion Criteria : * No Stroke history * patient who didn't signed consent Group 2 * Inclusion Criteria : * patient over 80 * ECG: sinusal rhythm * TTE : no left atrial dilatation * Exclusion Criteria : * atrial fibrillation history * TTE : Left atria \>25cm², \> 34m/m2), FEVG \< 50% * ECG : QRS \> 90 ms * cardiac pathologies (excepted hypertension and valvulopathies) * History of stroke and transient ischemic attack * patient who didn't signed consent Group 3 * Inclusion Criteria : * cryptogenic stroke or transient ischemic attack history before 50 yo * No AF history * Exclusion Criteria : * AF history * stroke or transient ischemic attack over 50 yo * patient who didn't signed consent

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Conditions

The condition(s) this trial relates to.

atrial fibrillation stroke disorder transient ischemic attack

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atrial fibrillation Stroke

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    5 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hôpital des charpennes

    RECRUITING

    Villeurbanne, 69100, France

  • Service d'urgences Neurovasculaires - service de neurologie vasculaire , Hôpital Pierre Wertheimer

    RECRUITING

    Bron, 69677, France

  • Service de médecine gériatrique Centre hospitalier Lyon Sud, Groupement hospitalier Sud

    RECRUITING

    Pierre-Bénite, 69495, France

  • Service de rythmologie, hôpital cardiologique Louis Pradel

    RECRUITING

    Bron, 69677, France

  • Service neurologie Centre hospitalier Fleyriat

    RECRUITING

    Bourg-en-Bresse, 01000, France

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